Upcoming events : save the date!

• HUPO World

When: 9th to 13th November, 2025
Where: Toronto, Canada
Booth: #303

Poster: 𝗣aper number 314: Fast and Robust Phosphoproteomics Sample Prep with AttractSPE® Disks C18 Tips for High Phosphopeptide Recovery and Identification.
Poster Viewing: Poster Session 3
Wednesday, Nov 12, 2025 | 1:15 PM – 3:15 PM

And join us for our breakfast seminar on Wednesday, November 12, 2025 | 8:00 – 9:00 am
“Sample Preparation methods for Glycoproteomics and Phosphoproteomics based on Affinisep BioSPE® membrane: Top-down Phospho-code analysis and automated workflow for N-glycan profiling“

Learn more about the breakfast seminar and register here.

• ItPA

When: 3rd to 5th December, 2025
Where: Rome, Italy

XIX Congress of the Italian Proteomics Association (ItPA), organized in collaboration with the Serbian Proteomics Association (SePA) and the Hellenic Proteomics Society (HPS)- Rome , 3rd – 5th December 2025.

• JFSM

When: 30th June to 03rd July 2025.
Where: Montpellier, France.

Meet us at booth #11!

• BSPR

When: 7th to 9th July, 2025
Where: Liverpool, UK
Domain: Bioanalysis
Visit us at booth 9.

Symposium organised by the British Society for Proteome Research.

• AMS

When: 20th to 23th July, 2025
Where: Atlanta, USA
Domain: Bioanalysis

• ASBMB

When: 17th to 21th August, 2025
Where: Cambridge, Mass, United States
Domain: Bioanalysis

• MSACL

When: 21th to 26th September, 2025
Where: Montréal, Canada
Domain: Bioanalysis

Meet us at booth #25

• CASSS

When: 23th to 26th September, 2025
Where: Costa Mesa, CA, United States
Domain: Mass Spectrometry in bioanalysis

Practical application of mass spectrometry (MS) in the biotechnology industry.

Visit us at booth #8

And join us for our lunch seminar on September 25, 2025 | 12:15-12:45 pm
“High Throughput Sample Preparation Method for MS-Based Proteomics: SPE Membrane Approaches for Peptide Cleanup and Enrichment”

Bottom-up LC-MS/MS workflows often require multistep sample preparation, followed by peptide cleanup to remove salts that otherwise cause ion suppression and reduce peptide identification rates. For proteoform analysis, enrichment of PTM-carrying peptides is also required to enable identification, localization, and quantification of modifications. Developing straightforward, automatable, and standardizable cleanup and enrichment methods is therefore essential to establish proteomics as a robust tool in drug discovery and diagnostics.

In this seminar, we will discuss how innovative SPE membrane technology, combined with two decades of experience in complex sample preparation, can help overcome key bottlenecks in MS-based proteomics.

One of the major challenges is high throughput single-cell and other low-input analyses, where consistent recovery from limited protein material is essential. Using optimized workflows, it was possible to obtain reproducible results across a 1 ng–10 µg input range, with up to 97% protein identification and < 3% RSD, demonstrating that even trace-level samples can be analyzed reliably.

Another critical area is glycoproteomics, where diverse glycan structures complicate enrichment and detection. Preliminary studies with SPE membrane-based methods achieved on average a five-fold increase in N-glycopeptide identifications from both cell lysates and plasma compared to unenriched samples, reaching performance levels comparable to or exceeding established HILIC-based approaches.

Phosphoproteomics presents a third challenge, as desalting steps often result in the loss of polar phosphopeptides. Here, membrane-based C18 formats enabled up to 2.4-fold more phosphopeptide identifications, with reproducibility below 10% RSD, while optimized acidification conditions further improved recovery of hydrophilic and singly phosphorylated peptides. Together, these examples illustrate how standardized SPE membrane workflows can provide efficient, reproducible, and high-throughput solutions for peptide desalting and PTM enrichment, supporting more robust and sensitive MS-based proteomics.

Save the date

• CEEPC

When: 14th to 17th October, 2025
Where: Budapest, Hungary

Central and Eastern European Proteomic Conference (19th CEEPC)