Ready-to-use kits for the analysis of Bisphenol from a variety of matrices: water, milk, canned food, urine, wines, beer, baby food …

Bisphenol A is an endocrine disruptor that can mimic the body’s own hormones and may lead to negative health effects.

Regulatory measures

The migration of Bisphenol A from the packaging to food is the main source of consumers’ exposure to BPA. So, the European Commission has defined a specific migration limit at a maximum level of 0.6 mg of BPA/kg of food (Directive 2011/8/EU of 28 January 2011). In addition, the directive prohibits the use of BPA to manufacture infant feeding bottles.

More recently, in April 2023, in a European Food Safety Authority (EFSA) communication, a re-evaluation of the full risk assessment.
Compared to their previous assessment in 2015, EFSA’s expert Panel significantly lowered the tolerable daily intake (TDI) for BPA, the amount that can be ingested daily over a lifetime without presenting an appreciable health risk.
EFSA’s scientists established a TDI of 0.2 ng/kg of body weight per day, replacing the previous temporary level of 4 µg/kg of body weight per day.
The newly established TDI is around 20,000 times lower.

This new recommendation should have an impact on the regulations concerning the above specific migration limit for food contact materials (FCM).
The European Commission and national authorities are responsible for setting limits on the amount of a chemical that may migrate from food packaging into food. So, appropriate regulatory measures should be taken to protect consumers.

About our product

AFFINIMIP® SPE Bisphenols are selective solid phase extraction cartridges that selectively clean and concentrate Bisphenol A and closely related structures such as BADGE prior to analysis by chromatography (LC, GC…).
This kit is very powerful to target a large range of bisphenol analogs with high sensitivity.

Good to know: LABERCA, a French National Reference Laboratory (NRL) has published a peer-reviewed scientific article targeting 18 “BPA-like” compounds using AFFINIMIP®SPE Bisphenols with recovery yields higher than 90% for each molecule.
In this publication, the 18 bisphenol analogues analyzed were:

  • Bisphenol B (BPB), bisphenol AP (BPAP), bisphenol AF (BPAF), bisphenol BP (BPBP), bisphenol C (BPC), bisphenol Cl2 (BPCl2), bisphenol E (BPE), bisphenol PH (BPPH),
  • Bisphenol S (BPS), bisphenol F (BPF), [4,4′-dihydroxydiphenyl ether (DHDPE), bisphenol FL (BPFL), bisphenol Z (BPZ), biphenyl-4,4′-diol (BP4,4′), bisphenol M (BPM), bisphenol P (BPP), bis-2(hydroxyphenyl)methane (BIS2) and biphenyl-2,2′-diol (BP2,2′).

Products list

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Selective SPE cartridges for Bisphenol A and analogues - 50/pk - 3mL PP cartridges

Ref. : FS106-03