18F Aromatic Nucleophilic Substitution
Purification of 18F radiotracer obtained from ammonium precursor by Aromatic Nucleophilic Substitution.
AFFINIMIP® SPE 18F – Aromatic Nucleophilic Substitution is a selective solid phase extraction cartridge used to purify rapidly and perfectly a 18F radiotracer synthesized from an aromatic nucleophilic substitution. The cartridge retains the ammonium-based precursor as well as the phenol- and dialkylamino-based impurities.
AFFINIMIP® SPE for purification of radiotracers is based on the affinity for the precursor. In the case of Aromatic Nucleophilic Substitution with 18F, impurities, Kryptofix and residual 18F are also retained on the cartridge, while the purified radiotracer is obtained after elution.
- Validated for radiotracers (FBA, Ethyl 4-Fluorobenzoate) issued from a SNAr with an ammonium precursor
- Rapid and simple method purification: No need for a preparative HPLC thanks to our All-in-One SPE
- Improved radiotracer purity: No traces of the 3 unwanted products (precursor and by-products) and low traces of Kryptofix and residual 18F were detected.
- Increased reliability of radiotracer production: Reduction of manual handling steps
- No cross contamination thanks to single use cartridges
Products list
| Product Name | Product Price | Product SKU | Cart Actions |
|---|---|---|---|
AFFINIMIP® SPE 18F Aromatic Nucleophilic Substitution0,7mL Reversible cartridges - 25/pk Ref. : RP100A-02 |
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9999 |
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AFFINIMIP® SPE 18F Aromatic Nucleophilic Substitution0,7mL Reversible cartridges - 10/pk Ref. : RP100A-01 |
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9998 |
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AFFINIMIP® SPE 18F Aromatic Nucleophilic Substitution2mL Reversible cartridges - 10/pk Ref. : RP100-01 |
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9997 |
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AFFINIMIP® SPE 18F Aromatic Nucleophilic Substitution2mL Reversible cartridges - 25/pk Ref. : RP100-02 |
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9996 |
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