Bisphenol A and other Bisphenols

Bisphenol A is an endocrine disruptor, which can mimic the body’s own hormones and may lead to negative health effects. The migration of Bisphenol A from the packaging to food is the main source of consumers’ exposure to BPA. So, the European commission has defined a specific migration limit at a maximum level of 0.6 mg of BPA/kg of food (Directive 2011/8/EU of 28 January 2011). In addition, the directive prohibits the use of BPA to manufacture infant feeding bottles.

We have developed our SPE solution to clean and concentrate selectively Bisphenol A and closely related structures such as BADGE before analysis by chromatography (LC, GC…). Discover our AFFINIMIP® SPE Bisphenols cartridge to learn more.

  • Endocrine Disruptors / 
  • Bisphenol A and other Bisphenols

Application Note AFFINIMIP®SPE Bisphenols for the total Bisphenol A determination in human urine

Human Urine
This application note describes a method to determine TOTAL Bisphenol A in Human urine. The combination of AFFINIMIP® SPE Bisphenols and LC-MS/MS enables the determination of very low concentration of Bisphenol A in urine.

DownloadPDF - 664.60kB
  • Endocrine Disruptors / 
  • Bisphenol A and other Bisphenols

Application note AFFINIMIP®SPE BISPHENOLS - COLA drinks

Cola drinks
This application note describes a method to determine Bisphenol A in Cola drinks. Recovery yields higher than 90% were obtained at concentration of 5ng/mL.

DownloadPDF - 602.67kB
  • Endocrine Disruptors / 
  • Bisphenol A and other Bisphenols

Application Note AFFINIMIP®SPE for the analysis of Bisphenol A in Beer at low concentrations

Beer matrices
This study describes the solid phase extraction of Bisphenol A from beer at low concentrations (1 and 2µg/L) using AFFINIMIP® SPE Bisphenols. HPLC analysis was performed with a flurescence detector. The results demonstrate the efficiency of the clean-up: high recovery yield (> 90%), a good repeatability and reproducibility were obtained.

DownloadPDF - 419.33kB
  • Endocrine Disruptors / 
  • Bisphenol A and other Bisphenols

Application Note AFFINIMIP®SPE Bisphenols - Red and white wines

Red and white wines
The determination of very low concentration (2µg/Kg) of Bisphenol A in Red and White Wines was carried out with a fluorescent detector after AFFINIMIP®SPE Bisphenols clean-up.

DownloadPDF - 1.23MB
  • Endocrine Disruptors / 
  • Bisphenol A and other Bisphenols

Application note AFFINIMIP®SPE BISPHENOLS - BISPHENOL A AND BADGE IN MILK

Bisphenol A and BADGE
This application note describes a method to determine Bisphenol A and BADGE in milk from plastic food packaging.

DownloadPDF - 648.33kB
  • Endocrine Disruptors / 
  • Bisphenol A and other Bisphenols

Application Note AFFINIMIP®SPE Bisphenols in Powdered Infant Formula at low concentrations

Powdered Infant Formula
This application note describes the analysis of very low concentration of BPA in powdered infant formula using AFFINIMIP®SPE Bisphenols cartridge. The method is perfectly suited for the quantification of Bisphenol A at very low concentration (2µg/L and 4µg/L), even using a fluorescence detector. The simple SPE procedure ensures mean recoveries > 95% and a very low relative standard deviation.

DownloadPDF - 492.86kB
  • Endocrine Disruptors / 
  • Bisphenol A and other Bisphenols

Application Note AFFINIMIP®SPE for the analysis of Bisphenol A in Infant Formula at low concentrations

Liquid Infant Formula
We demonstrate in this application note that a reliable quantification of Bisphenol A in liquid infant formula using fluorescence detection is possible, even at low concentrations(1 and 2µg/L). The use of AFFINIMIP®SPE Bisphenols enables to eliminate the tedious derivatization step required by gas chromatography.

DownloadPDF - 534.53kB
  • Endocrine Disruptors / 
  • Bisphenol A and other Bisphenols

Application note AFFINIMIP®SPE Bisphenols in Vegetable Puree

Vegetable Puree for Infants
This application note describes the analysis of very low concentration (3µg/kg and 24µg/kg) of BPA in vegetable puree for infant contained in a plastic food packaging using AFFINIMIP®SPE Bisphenols cartridge.

DownloadPDF - 670.43kB
  • Endocrine Disruptors / 
  • Bisphenol A and other Bisphenols

Application Note AFFINIMIP®SPE for the analysis of Bisphenol A from Canned Foods at low concentrations

Canned Foods
The tests were performed in canned peas and carrots and canned tuna and salmon. The results demonstrate the efficiency of the clean-up with fluorescence detection: high recovery yield (> 95%), a good repeatability and reproducibility were obtained in all the matrices.This method is also perfectly suitable for clean-up before GC-MS/MS or LC-MS/MS.

DownloadPDF - 664.12kB